Medusa

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Haunted Castle
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It's Medusa that starts out as stone in this game. She comes to life, laughs at you a few times, and starts to attack by throwing snakes onto the floor--them trekking along the ground--this while she moves back and forth unpredictably. If you can time your jumps to avoid the snakes, she won't be too much of a problem.

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Castlevania & Vampire Killer
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I can't imagine why Konami made her a giant head in this game--but this is what she looks like. She also lacks her ability to turn people into stone (which she regains in the later games). The only power she does have is to throw out little snakes from her head. The real danger is avoiding contact with her, as she takes up a lot of space while floating about.

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Castlevania III: Dracula's Curse
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Nintendo Power refers to this as "Sentinel Man," but it's probably safe to call it a mistake on their part. Regardless: She fires out little circular beams (gazes) from her eyes that turn you into stone if contact is made, and she throws little stalking snakes onto the ground. If she does manage to turn you into stone, she'll take out her bow and arrow and fire a shot your way. It won't break the stone-held hero in half (as it did in Clash of the Titans), but it's still heavily damaging. Medusa is only a mid boss in this game, so ducking and wailing on her will get the job done.

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Super Castlevania IV
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This form finally resembles the true image of Medusa, but it's too bad that she's a real a pushover. She comes charging out like she's ready for a fight, but then she backs off and starts slithering forward and back near the edge of the screen; from there, she'll throw little guided snakes onto the ground. If your attention shifts, she'll catch you off guard with a circular beam that'll turn you into stone; chances are, however, you will have killed her before she even gets the chance.

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Castlevania: Bloodlines
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Elizabeth Bartley summons Medusa to attack you when you reach the castle in England. Medusa attacks in a specific pattern: (1) She'll spit a short-lengthed, wavy flame forward for a time. (2) She'll attack with a longer flame, only this one will be lowered down to eye-level [like a drawbridge-lowering effect]. (3) A long tail whip. And (4) She'll take several short, stalking dashes, with claws extended.

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Dracula X: Rondo of Blood
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In this adventure, Medusa is nothing more than a pawn in Shaft's game. She's called upon as part of a set of four bosses. She has the stone glance available to her, and she also adds the ability to shoot out sets of spinning, homing-in snakes--in threes. She also employs a jumping tail-whip attack. This is perhaps the strongest Medusa has ever been in a Castlevania game.

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Akumajou Dracula X68000
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She's a bit more physical in this game. She retains her ability to shoot out a stone glaze that'll temporarily turn you to stone, and she can also loop three snakes in your direction while either on the ground or in the air. Most painfully, she can whip at you with her tail--this, too, while both in the air or on the ground. Her air attack is different in that she spins around before unleashing this nasty tail-whip.

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Castlevania: Symphony of the Night
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Medusa isn't as typical a foe this time around, as most of her offense is reliant on the sword. It'll be your mission to avoid her fierce overhead swipes and get in your licks. At any time, Medusa will use her powerful glaze in order to turn you to stone, where you'll be susceptible to devastating damage--mostly, she'll send two crisscrossing lightning blasts to rudely knock you out of that state. Her shield is protective, but it doesn't help much--in fact, it should be ineffective against a foe who stays in-close.

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Castlevania Legends
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They tried in this game. They really did. Medusa doesn't have any notable powers this time, but she's quick and fights with a sword. Unfortunately, she's only a mid boss, and they put a safe spot to the right of the room, making her a pushover yet again. She does fly off the screen in head form when defeated, though--probably Konami's way of saying that Legends was the origin of the pesky Medusa Heads.

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Castlevania: Legacy of Darkness
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Medusa shows up in the underground waterway. She'll always begin by throwing three or four snakes onto the ground to distract you. Her most frequent attack is to wind up and unleash a spinning tail-whip. If you strike her enough, she'll take out a shield and block your attacks, continuing with her own. If you strike her even more, she'll take out her bow and fire arrows in threes. As you get deeper into battle, she can project her vision into a ray, trapping you in a base of stone if you get caught in its path; she'll tail-whip you out of that state. Late in the battle, she'll begin disappearing from site by becoming a cloud formation. While she can't harm you in this state, she can reappear quickly with a surprise attack.

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Castlevania: Lament of Innocence
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It warms the heart to see Medusa return to giant-head form all these years later. It's almost a nice bit of continuity in her evolution since it predates the original Castlevania. Medusa has a number of attacks at her command: She can command the snakes on either side to lunge forward as a sort-of snake punch; she can also do this with both sides in succession for a one-two punch. She can rise into the air and spill a trail of her poisonous blood to keep you away. She can also rise into the air to drop a plethora of smaller snakes onto the ground to overwhelm you. She can, of course, project beams ("Turn to stone!") from her eyes that can temporarily turn you to stone; if successful, she'll roll herself into a giant ball and rebound around the room, a random number of times, to damage you heavily. Finally, when her energy is low, she'll command large stones ("Damn you!") to surround herself before firing them toward you one after another. There are two differences in "Crazy Mode": She'll do the snake punch in seven-step combos, and she'll do a stone gaze as part of the stone-throwing attack.

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Castlevania: Portrait of Ruin
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Medusa, one of three gorgon sisters, returns to two dimensions in her most recognizable form. For her fans, it was worth the wait, as the doomed snake woman is arguably at her offensive peak. There are in total five separate maneuvers in her arsenal: Her arms morphed into snakes and thrust forward, she'll rush in with a stalking dash. She'll extend her exceedingly large snakey frame to wave along the ground and temporarily remain in place so that the arches protrude and continue to damage heroes. She'll release from her head a flurry of gold stone-inducing Medusa Heads. And, as a paired attacked, she'll unleash her stone gaze, which will render an obvious effect on heroes looking her way, and she'll then transform into a large snake, vanish from sight, and then come in with a surprise cobra-like charging snap.

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Castlevania: Order of Shadows
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While it's surely not the hideous snake-woman's most powerful form, it's certainly one of the more stacked in terms of abilities. Particularly, Medusa is more agile than ever before, able to leapfrog the hero for a more evasive approach. The sword isn't for show, as Medusa will never hesitate to plunge it into Desmond if he decides to get too close. Present, also, is her ability to fire out from her eyes a beam which upon contact will temporarily stone the hero, who will be increasingly vulnerable. Rounding out the assault is Medusa's ability to use her head--that is, to command a group of Medusa heads to wave forward and generally crowd the area.

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